Publications |
* = Corresponding Author |
F. Xu, L. Chen,* D. Lehnherr,* F. Lévesque
Org. Process Res. Dev. 2025, 29, 872—880. [PDF] doi: 10.1021/acs.oprd.4c00532
Z. J. Oliver, D. J. Abrams, L. Cardinale, C.-J. Chen, G. L. Beutner, S. Caille, B. Cohen, L. Deng, M. Diwan, M. O. Frederick, K. Harper, J. M. Hawkins, D. Lehnherr, C. Lucky, A. Meyer, S. Noh, D. Nunez, K. Quasdorf, J. Teli, S. S. Stahl,* M. Schreirer*
ACS Cent. Sci. 2025, 11, 528—538. [PDF] doi: 10.1021/acscentsci.4c01733
H. Yang,* D. Lehnherr*
Nat. Synth. 2025, 4, 414—416. [PDF] doi: 10.1038/s44160-024-00733-z
A. C. Ferretti,* B. Cohen, L. Deng, M. Diwan, M. O. Frederick, D. Lehnherr
Org. Process Res. Dev. 2025, 29, 322—332. [PDF] doi: 10.1021/acs.oprd.4c00353
D. Lehnherr,* L. Chen,* F. Lévesque, C. Nietupski, M. Weisel, V. Mdluli, K. Mattern, B. M. Armstrong, T. Chen, R. D. Cohen
Org. Process Res. Dev. 2025, 29, 100—113. [PDF] doi: 10.1021/acs.oprd.4c00372
R. Maity, O. Dungan, F. A. Perras, J. Li, D. Liu, S. Ren, D. Lehnherr, Z. Huang, E. M. Phillips, M. Adeyemo, J. Frimpong, T. Quainoo, Z.-F. Liu, L. Luo*
J. Am. Chem. Soc. 2024, 146, 34141—34151. [PDF] doi: 10.1021/jacs.4c13857
V. Mdluli, D. Lehnherr,* Y.-h. Lam,* M. T. Chaudhry, J. A. Newman, J. O. DaSilva, E. L. Regalado
Chem. Sci. 2024, 15, 5980—5992. [PDF] doi: 10.1039/D3SC05357A
D. Lehnherr,* L. Chen*
Org. Process Res. Dev. 2024, 28, 338—366. [PDF] doi: 10.1021/acs.oprd.3c00340
Accelerating Pharmaceutical Process Development with an Acoustic Droplet Ejection-Multiple Reaction Monitoring-Mass Spectrometry WorkflowH. Hu,*, A. N. Singh, D. Lehnherr, V. Mdluli, S. W. Chun, A. M. Makarewicz, J. R. Gouker, O. Ukaegbu, S. Li, X. Wen, D. G. McLaren, J. E. Velasquez, J. C. Moore, S. Galanie, E. Appiah-Amponsah, E. L. Regalado
Anal. Chem. 2024, 96, 1138—1146. [PDF] doi: 10.1021/acs.analchem.3c04211
• Highlighted on Cover
B. K. Malviya, C. Bottecchia, K. Stone, D. Lehnherr, F. Lévesque, C. O. Kappe, D. Cantillo*
Org. Process Res. Dev. 2023, 27, 2183—2191. [PDF] doi: 10.1021/acs.oprd.3c00332
L. Cardinale, S. S. Stahl,* D. Kalyani,* D. Lehnherr*
Adv. Catal. 2023, 72, 57—102. [PDF] doi: 10.1016/bs.acat.2023.07.009
J. Twilton,‡ M. R. Johnson,‡ V. Sidana, M. C. Franke, C. Bottecchia, D. Lehnherr, F. Lévesque, S. M. M. Knapp, L. Wang, J. B. Gerken, C. M. Hong, T. P. Vickery, M. D. Weisel, N. A. Strotman, D. J. Weix,* T. W. Root,* S. S. Stahl* (‡ = equal contribution)
Nature 2023, 623, 71—76. [PDF] doi: 10.1038/s41586-023-06534-2
R. Motz, A. C. Sun, D. Lehnherr, S. Ruccolo*
ACS Org. Inorg. Au 2023, 3, 266—273. [PDF] doi: 10.1021/acsorginorgau.3c00019
Copper-Enabled Photo-Sulfonylation of Aryl Halides Using Alkylsulfinates V. Mdluli, D. Lehnherr,* Y.-h. Lam,* Y. Ji, J. Newman, J. Kim
Adv. Synth. Catal. 2023, 26, 3876—3886. [PDF] doi: 10.1002/adsc.202300257
• Highlighted on Cover
• Highlighted in Synform
B. Cohen*, D. Lehnherr, M. Sezen-Edmonds, J. H. Forstater, M. O. Frederick, L. Deng, A. C. Ferretti, K. Harper, M. Diwan
Chem. Eng. Res. Des. 2023, 192, 622—637. [PDF] doi: 10.1016/j.cherd.2023.02.050
V. Mdluli, D. Lehnherr*
In Comprehensive Chirality, 2nd ed.; Cossy, J., Ed.; Academic Press, 2024, 206—240. [PDF] doi: 10.1016/B978-0-32-390644-9.00032-9
J. Rein, S. Lin,* D. Kalyani,* D. Lehnherr*
ACS Symposium Series, Vol. 1419, 2022, 167—187. [PDF] doi: 10.1021/bk-2022-1419.ch010
In The Power of High-Throughput Experimentation: General Topics and Enabling Technologies for Synthesis and Catalysis (Volume 1); M. H. Emmert, M. Jouffroy, D. C. Leitch, Eds.; ACS Symposium Series, Vol. 1419, American Chemical Society, 2022.
eBook ISBN: 9780841297562. Hardcover ISBN13: 9780841297579.
Z. W. Schroeder, R. McDonald, M. J. Ferguson, W. A. Chalifoux, R. R. Tykwinski, D. Lehnherr*
J. Org. Chem. 2022, 87, 16236—16249. [PDF] doi: 10.1021/acs.joc.2c01755
C. Bottecchia,* D. Lehnherr,* F. Lévesque, M. Reibarkh, Y. Ji, V. L. Rodrigues, H. Wang, Y.-h. Lam, T. P. Vickery, B. M. Armstrong, K. A. Mattern, K. Stone, M. K. Wismer, A. N. Singh, E. L. Regalado, K. M. Maloney, N. A. Strotman
Org. Process Res. Dev. 2022, 26, 2423—2437. [PDF] doi: 10.1021/acs.oprd.2c00111
• Selected as ACS Editors' Choice (open acess for a limited time)
I. Papadopoulos, S. R. Reddy, P. B. Coto*, D. Lehnherr, D. Thiel, M. Thoss, R. R. Tykwinski, D. M. Guldi*
J. Phys. Chem. Lett. 2022, 13, 5094—5100. [PDF] doi: 10.1021/acs.jpclett.2c01395
H. Yang,* Z. Huang, D. Lehnherr,* Y.-h. Lam, S. Ren, N. A. Strotman
J. Am. Chem. Soc. 2022, 144, 5010—5022. [PDF] doi: 10.1021/jacs.1c13265
W. Zhang, L. Lu, W. Zhang, Y. Wang, S. D. Ware, J. Mondragon, J. Rein, N. Strotman, D. Lehnherr, K. A. See,* S. Lin*
Nature 2022, 604, 292—297. [PDF] doi: 10.1038/s41586-022-04540-4
• Highlighted in Synform
N. E. S. Tay, D. Lehnherr,* T. Rovis*
Chem. Rev. 2022, 122, 2487—2649. [PDF] doi: 10.1021/acs.chemrev.1c00384
• Part of special issue on "Photochemical Catalytic Processes".
C. Bottecchia,‡,* F. Lévesque,‡,* J. P. McMullen, Y. Ji, M. Reibarkh, F. Peng, L. Tan, G. Spencer, J. Nappi, D. Lehnherr, K. Narsimhan, M. K. Wismer, L. Chen, Y. Lin, S. M. Dalby (‡ = equal contribution)
Org. Process Res. Dev. 2022, 26, 516—524. [PDF] doi: 10.1021/acs.oprd.1c00240
Y. Ji,* C. Bottecchia, F. Lévesque, K. Narsimhan, D. Lehnherr, J. P. McMullen, S. M. Dalby, K.-J. Xiao, M. Reibarkh*
J. Org. Chem. 2022, 87, 2055—2062. [PDF] [Supporting Information] doi: 10.1021/acs.joc.1c01465
J. Rein, J. R. Annand, M. K. Wismer, J. Fu, J. C. Siu, A. Klapars, N. A. Strotman, D. Kalyani,* D. Lehnherr,* S. Lin*
ACS Cent. Sci. 2021, 7, 1347—1355. [PDF] [Supporting Information] doi: 10.1021/acscentsci.1c00328
• HTe—Chem is now available from Analytical Sales.
Development of a Green & Sustainable Manufacturing Process for Gefapixant Citrate K. Basu,* D. Lehnherr,* G. E. Martin, R. A. Desmond, Y.-h. Lam, F. Peng, J. Y. L. Chung, R. Arvary, M. A. Zompa, S.-W. Zhang, J. Liu, Z. E. X. Dance, P. Larpent, R. D. Cohen, F. J. Guzman, N. J. Rogus, M. J. Di Maso, H. Ren, K. M. Maloney
Org. Process Res. Dev. 2020, 24, 2462—2477. [PDF] [Supporting Information] doi: 10.1021/acs.oprd.0c00246
• Featured on Issue Cover
Development of a Green & Sustainable Manufacturing Process for Gefapixant Citrate F. Peng,* G. R. Humphrey, K. Maloney, D. Lehnherr, M. Weisel, F. Lévesque, J. R. Naber, A. P. J. Brunskill, P. Larpent, S.-W. Zhang, A. Y. Lee, R. A. Arvary, C. H. Lee, D. Bishara, K. Narsimhan, E. Sirota, M. Whittington.
Org. Process Res. Dev. 2020, 24, 2453—2461. [PDF] [Supporting Information] doi: 10.1021/acs.oprd.0c00241
• Featured on Issue Cover
Development of a Green & Sustainable Manufacturing Process for Gefapixant Citrate H. Ren,* K. M. Maloney,* K. Basu, M. J. Di Maso, G. R. Humphrey, F. Peng, R. Desmond, D. A. L. Otte, E. Alwdi, W. Liu, S.-W. Zhang, S. Song, R. A. Arvary, M. A. Zompa, D. Lehnherr, G. E. Martin, H. Yao, D. Chang, A. E. Mohan, F. J. Guzman, L. Jellett, A. Y. Lee, G. Spencer, E. S. Fisher, J. R. Naber, H. Gao, S. Lohani, R. T. Ruck, L.-C. Campeau
Org. Process Res. Dev. 2020, 24, 2445—2452. [PDF] [Supporting Information] doi: 10.1021/acs.oprd.0c00248
• Featured on Issue Cover
J. O. DaSilva,* D. Lehnherr, J. Liu, R. Bennett, I. A. H. Ahmad, M. Hicks, B. F. Mann, D. A. DiRocco, E. L. Regalado*
ACS Sustainable Chem. Eng. 2020, 8, 6011—6021. [PDF] [Supporting Information] doi: 10.1021/acssuschemeng.0c00777
M. C. Nicastri, D. Lehnherr,* Y.-h. Lam, D. A. DiRocco, T. Rovis*
J. Am. Chem. Soc. 2020, 142, 987—998. [PDF] [Supporting Information] doi: 10.1021/jacs.9b10871
D. Lehnherr,* Y.-h. Lam, M. C. Nicastri, J. Liu, J. A. Newman, E. L. Regalado, D. A. DiRocco, T. Rovis*
J. Am. Chem. Soc. 2020, 142, 468—478. [PDF] [Supporting Information] doi:10.1021/jacs.9b10870
D. Lehnherr,* X. Wang,* F. Peng, M. Weisel, M. Reibarkh, K. M. Maloney
Organometallics 2019, 38, 103—118. [PDF] [Supporting Information] doi: 10.1021/acs.organomet.8b00543
• Part of special issue on "The Roles of Organometallic Chemistry in Pharmaceutical Research and Development".
D. Lehnherr,‡,* Y. Ji,‡,* A. J. Neel, R. D. Cohen, A. P. J. Brunskill, J. Yang, M. Reibarkh
(‡ = equal contribution)
J. Am. Chem. Sci. 2018, 140, 13843—13853. [PDF] [Supporting Information] doi: 10.1021/jacs.8b08596
S. J. Hein, D. Lehnherr, H. Arslan, F. J. Uribe-Romo, W. R. Dichtel*
Acc. Chem. Res. 2017, 50, 2776—2788. [PDF] doi: 10.1021/acs.accounts.7b00385
S. J. Hein, D. Lehnherr, W. R. Dichtel*
Chem. Sci. 2017, 8, 5675—5681. [PDF] [Supporting Information] doi: 10.1039/c7sc01625e
J. L. Marshall, D. Lehnherr, B. D. Lindner, R. R. Tykwinski*
ChemPlusChem 2017, 82, 967—1001. [PDF] doi: 10.1002/cplu.201700168
• Part of special issue on "Novel Aromatics: From Synthesis to Applications".
D. Lehnherr, J. M. Alzola, C. R. Mulzer, S. J. Hein, W. R. Dichtel*
J. Org. Chem. 2017, 82, 2004—2010. [PDF] [Supporting Information] doi: 10.1021/acs.joc.6b02840
• Highlighted in Synfacts
D. Lehnherr, M. Adam, A. H. Murray, R. McDonald, F. Hampel, R. R. Tykwinski*
Can. J. Chem. 2017, 95, 303—314. [PDF] [Supporting Information] doi: 10.1139/cjc-2016-0450
• Part of special issue dedicated to Prof. Reginald Mitchell.
M. Garcia-Borràs, A. Konishi, A. Waterloo, Y. Liang, Y. Cao, C. Hetzer, D. Lehnherr, F. Hampel, K. N. Houk,* R. R. Tykwinski*
Chem. Eur. J. 2017, 23, 6111—6117. [PDF] [Supporting Information] doi: 10.1002/chem.201604099
• Part of special issue on "Cooperative Effects in Chemistry".
C. R. Kennedy,‡ D. Lehnherr,‡ N. S. Rajapaksa, D. D. Ford, Y. Park, E. N. Jacobsen*
(‡ = equal contribution)
J. Am. Chem. Soc. 2016, 138, 18122—18127. [PDF] [Supporting Information] doi: 10.1002/jacs.6b09205
D. Lehnherr, C. Chen, Z. Pedramrazi, C. R. DeBlase, J. M. Alzola, I. Keresztes, E. B. Lobkovsky, M. F. Crommie,* W. R. Dichtel*
Chem. Sci. 2016, 7, 6357—6364. [PDF] [Supporting Information] doi: 10.1039/C6SC02520J
• Highlighted in Synfacts
D. Lehnherr, D. D. Ford, A. Bendelsmith, C. R. Kennedy, E. N. Jacobsen*
Org. Lett. 2016, 18, 3214—3217. [PDF] [Supporting Information] doi: 10.1021/acs.orglett.6b01435h
• Highlighted in Synfacts
D. D. Ford, D. Lehnherr, C. R. Kennedy, E. N. Jacobsen*
ACS Catal. 2016, 6, 4616—4620. [PDF] [Supporting Information] doi: 10.1021/acscatal.6b01384
D. D. Ford,‡ D. Lehnherr,‡ C. R. Kennedy, E. N. Jacobsen*
(‡ = equal contribution)
J. Am. Chem. Soc. 2016, 138, 7860—7863. [PDF] [Supporting Information] doi: 10.1021/6b04686
J. Zirzlmeier, R. Casillas, S. R. Reddy, P. B. Coto, D. Lehnherr, E. T. Chernick, I. Papadopoulos, M. Thoss*, R. R. Tykwinski*, D. M. Guldi*
Nanoscale 2016, 8, 10113—10123. [PDF] [Supporting Information] doi: 10.1039/C6NR02493a
Regioselective Synthesis of Polyheterohalogenated Naphthalenes via the BenzannulationD. Lehnherr, J. M. Alzola, E. B. Lobkovsky, W. R. Dichtel*
Chem. Eur. J. 2015, 21, 18122—18127. [PDF] [Supporting Information] doi: 10.1002/chem.2001503418
• Featured on Issue Cover
J. Zirzlmeier, D. Lehnherr, P. B. Coto, E. T. Chernick, R. Casillas, B. Basel, M. Thoss*, R. R. Tykwinski*, D. M. Guldi*
Proc. Natl. Acad. Sci. U.S.A. 2015, 112, 5325—5330 [PDF] [Supporting Information] doi: 10.1073/pnas.1422436112
A. R. Waterloo, A.-C. Sale, D. Lehnherr, F. Hampel, R. R. Tykwinski*
Beilstein J. Org. Chem. 2014, 10, 1692—1705 [PDF] [Supporting Information] doi: 10.3762/bjoc.10.178
• Part of special issue on “Functionalized Carbon-Nanomaterials” (Guest Editor: Prof. Anke Krueger).
D. Lehnherr, A. Waterloo, K. P. Goetz, M. M. Payne, F. Hampel, J. E. Anthony,* O. D. Jurchescu,* R. R. Tykwinski*
Org. Lett. 2012, 14, 3660—3663 [PDF] [Supporting Information] doi: 10.1021/ol301503k
D. Lehnherr, R. Hallani, R. McDonald, J. E. Anthony,* R. R. Tykwinski*
Org. Lett. 2012, 14, 62—65 [PDF] [Supporting Information] doi: 10.1021/ol202843x
D. Lehnherr, R. R. Tykwinski*
Aust. J. Chem. 2011, 64, 919—929 [PDF] doi: 10.1071/CH11169
D. Lehnherr, A. H. Murray, R. McDonald, R. R. Tykwinski*
Angew. Chem. Int. Ed. 2010, 49, 6190—6194 [PDF] [Supporting Information] doi: 10.1002/anie.201000555
D. Lehnherr, R. R. Tykwinski*
Materials 2010, 3, 2772—2800 [PDF] doi: 10.3390/ma3042772
• Review as part of the special issue on “Conjugated Oligomers” (Guest Editor: Prof. Herbert Meier).
D. Lehnherr, A. H. Murray, R. McDonald, M. J. Ferguson, R. R. Tykwinski*
Chem. Eur. J. 2009, 15, 12580—12584 [PDF] [Supporting Information] doi: 10.1002/chem.200902179
D. Lehnherr, J. Gao, F. A. Hegmann,* R. R. Tykwinski*
J. Org. Chem. 2009, 74, 5017—5024 [PDF] [Supporting Information] doi: 10.1021/jo9007089
D. Lehnherr, R. McDonald, M. J. Ferguson, R. R. Tykwinski*
Tetrahedron 2008, 64, 11449—11461 [PDF] [Supporting Information] doi: 10.1016/j.tet.2008.09.041
• Part of “The Synthesis of Carbon-Rich Nanomolecules” symposia in print.
D. Lehnherr, J. Gao, F. A. Hegmann,* R. R. Tykwinski*
Org. Lett. 2008, 10, 4779—4782 [PDF] [Supporting Information] doi: 10.1021/ol801886h
D. Lehnherr, R. McDonald, R. R. Tykwinski*
Org. Lett. 2008, 10, 4163—4166 [PDF] [Supporting Information] doi: 10.1021/ol801464k
D. Lehnherr, R. R. Tykwinski*
Org. Lett. 2007, 9, 4583—4586 [PDF] [Supporting Information] doi: 10.1021/ol702094d
D. Mitchell, M. Lukeman, D. Lehnherr, P. Wan*
Org. Lett. 2005, 7, 3387—3389 [PDF] [Supporting Information] doi: 10.1021/ol051381u
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